After upgrading from ie6 to ie7 for our crossover pro users, we found that they were all getting the runonce page ( and couldn't get rid of it. Searching the codeweaver support site didn't help, the only advice given there was to ignore the issue. After looking around a bit I found that the way to remove it is to fool ie into thinking it's already displayed it, using regedit as listed in the comments in this page
I ran regedit using cxrun and added these values to the registry.
[HKEY_CURRENT_USER\Software\Microsoft\Internet Explorer\Main] "RunOnceHasShown"=dword:00000001 "RunOnceComplete"=dword:00000001

After that I decided to change the default search to google using regedit as well (since changing it doesn't work from crossover)

[HKEY_CURRENT_USER\Software\Microsoft\Internet Explorer\SearchScopes\{2FEDD0BC-4D55-413C-8B59-BFE70133A2CB}] "DisplayName"="Google" "URL"="{searchTerms}&{language}&ie={inputEncoding}&oe={outputEncoding}&startIndex={startIndex?}&num=20&startPage={startPage}"
After that, ie7 opens to our specified homepage and the search bar goes to google as it should.

About the Author...